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William R Freeman Selected Research

3- (1- (3- hydroxy- 4- methoxyphenyl)methylidene)- 6- methylchroman- 4- one

7/2008Toxicity and intraocular properties of a novel long-acting anti-proliferative and anti-angiogenic compound IMS2186.

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William R Freeman Research Topics

Disease

45Macular Degeneration (Age-Related Maculopathy)
11/2023 - 10/2002
24Macular Edema
11/2022 - 09/2003
20Choroidal Neovascularization
10/2019 - 10/2002
19Retinitis
01/2015 - 02/2002
17Epiretinal Membrane (Epiretinal Membranes)
07/2019 - 09/2003
11Diabetic Retinopathy (Retinopathy, Diabetic)
01/2023 - 06/2011
8Uveitis
06/2012 - 09/2003
7Retinal Perforations
07/2016 - 08/2002
6Inflammation (Inflammations)
10/2021 - 03/2006
6Cataract (Cataracts)
11/2020 - 02/2002
6Cytomegalovirus Retinitis
04/2011 - 09/2002
6Acquired Immunodeficiency Syndrome (AIDS)
02/2007 - 06/2002
5Infections
01/2023 - 02/2002
5Retinal Diseases
10/2021 - 01/2002
5Retinal Detachment (Retinal Detachments)
12/2020 - 09/2002
5Cicatrix (Scar)
11/2018 - 09/2010
4Geographic Atrophy
07/2023 - 09/2009
4Ganglion Cysts (Ganglion)
11/2021 - 12/2009
4Hemorrhage
03/2018 - 10/2004
4Burns
06/2011 - 10/2004
4Neoplasms (Cancer)
07/2008 - 02/2002
3Retinal Vein Occlusion
12/2022 - 02/2008
3Retinal Neovascularization
11/2022 - 01/2002
3Edema (Dropsy)
11/2018 - 10/2007
3Glaucoma
11/2018 - 09/2002
3Melanoma (Melanoma, Malignant)
04/2018 - 09/2002
3Microaneurysm
05/2013 - 06/2011
3Cysts
06/2012 - 01/2008
3Gliosis
09/2010 - 04/2006
2Choroidal Effusions
01/2023 - 02/2002
2Ischemia
12/2022 - 03/2021
2Blindness (Hysterical Blindness)
11/2021 - 10/2016
2Pain (Aches)
06/2021 - 12/2005
2Disease Progression
06/2021 - 03/2004
2Proliferative Vitreoretinopathy
01/2018 - 01/2012
2Choroid Diseases
12/2015 - 12/2012
2Papilledema
01/2015 - 11/2007
2Vision Disorders (Hemeralopia)
01/2014 - 06/2012
2Toxic Optic Neuropathy
02/2013 - 01/2012
2Uveal melanoma
09/2002 - 02/2002
1COVID-19
01/2023
1Retinal Dystrophies
01/2023
1Vascular Diseases (Vascular Disease)
12/2022
1Retinal Vasculitis
10/2021
1Late-Onset Retinal Degeneration
06/2021
1Atrophy
06/2021

Drug/Important Bio-Agent (IBA)

53Retinaldehyde (Retinal)IBA
01/2023 - 02/2002
13Fluorescein (Funduscein)FDA LinkGeneric
12/2022 - 10/2002
10Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2022 - 08/2008
9Bevacizumab (Avastin)FDA Link
04/2017 - 07/2007
7afliberceptIBA
04/2019 - 03/2015
7Triamcinolone Acetonide (Azmacort)FDA LinkGeneric
01/2017 - 03/2006
5Triamcinolone (Aristocort)FDA Link
01/2017 - 02/2007
5SteroidsIBA
06/2012 - 06/2004
4LipidsIBA
11/2022 - 04/2011
4Cidofovir (Vistide)FDA Link
01/2015 - 10/2003
4prinomastat (Ag3340)IBA
10/2004 - 01/2002
3Biomarkers (Surrogate Marker)IBA
01/2023 - 03/2021
3Ranibizumab (Lucentis)FDA Link
08/2020 - 06/2012
3Indocyanine Green (Cardio-Green)FDA LinkGeneric
11/2017 - 12/2002
3ProdrugsIBA
01/2012 - 04/2011
2Pentosan Sulfuric Polyester (Pentosan Polysulfate)FDA Link
11/2023 - 01/2023
2Brimonidine Tartrate (Alphagan)FDA LinkGeneric
07/2023 - 01/2021
2SiliconIBA
11/2022 - 01/2018
2Lidocaine (Xylocaine)FDA LinkGeneric
06/2021 - 12/2005
2N-acetyltryptophanamide (NATA)IBA
01/2020 - 01/2016
2Endothelial Growth FactorsIBA
03/2018 - 09/2015
2Dexamethasone (Maxidex)FDA LinkGeneric
01/2018 - 12/2014
2Coloring Agents (Dyes)IBA
11/2017 - 10/2009
2brincidofovirIBA
01/2015 - 12/2011
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2014 - 08/2008
2Silicone OilsIBA
06/2010 - 11/2005
2Retinal Pigments (Pigments, Visual)IBA
09/2009 - 10/2002
2DNA (Deoxyribonucleic Acid)IBA
04/2006 - 02/2006
2Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
02/2006 - 02/2004
2Antiviral Agents (Antivirals)IBA
11/2004 - 02/2002
2Matrix Metalloproteinases (MMPs)IBA
10/2004 - 02/2002
1faricimabIBA
01/2023
1SodiumIBA
01/2023
1Small Interfering RNA (siRNA)IBA
11/2022
1IntegrinsIBA
11/2022
1iridium oxideIBA
11/2021
1brolucizumabIBA
10/2021
1proxymetacaine (Alcaine)FDA LinkGeneric
06/2021
1Hemoglobins (Hemoglobin)IBA
03/2021
1CholesterolIBA
03/2021
1Triglycerides (Triacylglycerol)IBA
03/2021

Therapy/Procedure

32Lasers (Laser)
12/2022 - 09/2002
20Therapeutics
10/2021 - 02/2002
13Injections
07/2023 - 02/2002
10Vitrectomy
04/2021 - 08/2002
9Intravitreal Injections
01/2023 - 02/2002
7Traction
07/2016 - 08/2008
7Highly Active Antiretroviral Therapy (HAART)
04/2011 - 06/2002
5Light Coagulation
08/2014 - 10/2002
4Semiconductor Lasers
02/2011 - 10/2002
3Aftercare (After-Treatment)
06/2013 - 10/2002
2Visual Prosthesis
12/2018 - 10/2016
1Tissue Transplantation
01/2023
1Electrodes (Electrode)
11/2021